IS Ecp1 -Mediated Transposition of qnrB -Like Gene in Escherichia coli

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ISEcp1-mediated transposition of qnrB-like gene in Escherichia coli.

A novel QnrB-like plasmid-mediated resistance determinant, QnrB19, was identified from an Escherichia coli clinical isolate from Colombia. Its gene was associated with an ISEcp1-like insertion element that did not act as a promoter for its expression. Using an in vitro model of transposition, we showed that the ISEcp1-like element was able to mobilize the qnrB19 gene.

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2008

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.00349-08